Arteriovenous Malformation (AVM)
Arteriovenous Malformation (AVM) is a complex tangle
of thin-walled blood vessels that can break more easily
than normal, healthy vessels. AVMs are commonly
associated with strokes at younger ages (20 40
years old), but the onset of symptoms is usually not
as fast as the ones produced by an aneurysm rupture.
Treatments
Embolization for Preoperative or Permanent Occlusion
A procedure involving the insertion of a micro catheter
through the femoral artery that is threaded through
the arterial network until the tip reaches the site
of the abnormal feeding arteries to the AVM. Preoperative
embolization or closure of AVMs is acquired through
the use of therapeutic liquid embolic agents and coils.
Microsurgery
Depending upon the size and location of the AVM, it
can be removed surgically.
Stereotactic Radiosurgery
A non-invasive therapeutic approach, it involves aiming
a narrow beam of highly focused radiation directly on
the AVM. The high dose of radiation damages the walls
of the irregular blood vessels causing them to shrivel
up and eventually close off.
Combination Therapies
Treatment of brain AVMs has been greatly enhanced by
incorporating a combined modality approach. For example,
in patients where embolization is used prior to surgery,
the subsequent operation is made significantly easier
than if the embolization had not been performed. The
operating time can be reduced, as can the intraoperative
blood loss during the resection of these lesions. In
addition, if the AVM is reduced in size significantly
either through surgery or embolization, the lesion may
then be treated with stereotactic radiosurgery. Due
to the resulting changes in the blood vessel walls,
the AVM may be obliterated over the course of 2-3 years.
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