Glioblastoma Multiforme (GBM)
The glioblastoma multiforme is one of the most malignant
brain tumors. These tumors are a form of astrocytoma.
These tumors can spread within the brain and spinal
cord. They have also been known to spread outside of
the nervous system though this is very rare. The mean
age when these tumors are discovered is in patients
in their mid-fifties. They are more common in men than
women. These tumors tend to grow quickly and produce
symptoms earlier than the lower grade asytrocytomas.
Glioblastoma Multiforme (GBM) Symptoms
Due to the rapid growth of the glioblastoma multiforme,
the first symptoms often are related to increased pressure
in the skull. Headache is common, seizures may occur,
changes in personality and weakness that might be mistaken
for a stroke can all occur.
Glioblastoma Multiforme (GBM) Diagnosis
While a careful history and physical examination are
the first step in diagnosis, imaging studies are the
next most important step. CT
scanning and MRI
scanning are both good methods to demonstrate the presence
of a tumor. The MRI gives more information. In both
cases the scans should be done without and with intravenous
contrast enhancement.
Glioblastoma Multiforme (GBM) Treatment
Surgery to remove as much tumor as safely possible
is the usual first step in the treatment of glioblastoma
multiforme. Occasionally, the location of the tumor
or the age of the patient lead the surgeon away from
major surgery and towards a biopsy. Radiation
therapy almost always follows surgery. Chemotherapy
may also be used. Occasionally stereotactic
radiosurgery is used to try to treat residual tumor.
These tumors frequently recur despite all of the above
treatments. Depending on the individual case, re-operation,
further chemotherapy and stereotactic radiosurgery might
be used to slow tumor growth.
Call 1-800-411-CINN or the location
nearest you between 8 AM and 5:30 PM Central
Time, Monday through Friday to schedule an initial consultation
with a CINN
physician.
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