Germinoma

The germinoma is a type of germ cell tumor. These brain tumors arise from sex cells. Germinomas tend to occur in younger patients. The most common location is in the midline of the brain. In male patients, the tumors tend to be found in the pineal region (in the middle back portion of the brain). In female patients, germinomas tend to be found in the suprasellar region (at the base of the skull near the front).

Germinoma Symptoms

The symptoms of a germinoma are related to its location, size and speed of growth. A common feature is hydrocephalus (blockage of spinal fluid within the brain). This can cause headaches, nausea, vomiting and double vision. Tumors near the optic nerves (suprasellar tumors) can cause loss of vision.

Germinoma Diagnosis

A careful history and physical examination is the first step in diagnosis. An MRI scan performed without and with intravenous contrast enhancement is the best diagnostic test. Sometimes an MRI scan of the entire spine will be performed. Germinomas can sometimes be diagnosed by examination of the spinal fluid for cells.

Germinoma Treatment

Depending on the location of the brain tumor, surgery may be used for both diagnostic biopsy and resection. The germinoma responds well to radiation therapy. Chemotherapy may also be used in select patients.

Call 1-800-411-CINN or the location nearest you between 8 AM and 5:30 PM Central Time, Monday through Friday to schedule an initial consultation with a CINN physician.